I am extremely upset at myself for letting a similar but very serious threat get to my pup again. Tasty, liver-flavored chewable tablet is easy to administer. I have been feeding her some white rice hoping it improves. Itching has decreased immensely. She is now 2 1/2 months post event. By overloading chloride into these worms, it affects the electrical activity within their nervous system, causing muscle paralysis and death. Vet office said make sure to give with food. Another call to vet asking for an appt - seems like an an emergency now? Buddy 8 year old male Boxer formerly energetic and playful. Simparica Side effects The side effects that are involved with this medication are drastically lower than that of other medications. My 1 year old Italian Spinone puppy has been losing hair on her back and has a big ear infection. 38 results for "simparica trio for dogs" RESULTS. No more Simperica for my dog! They said , he has a Autoimmune Hemolytic anemia . My personal dog has had no issues at all, and she's been on it for nearly two years. If you accidentally ingest a pet medication, call your physician or the national Poison Control Center hotline at 800-222-1222. She keeps running through the house as though looking for something. Were now into day 2 no changes except add a continuous walking into the next room turn around come back sit down just to repeat several more times. I am interested in the petition and the company's response. ALL oral tick meds are in the same class of drugs, so cannot give anything with that in it. I am also very worried about him. Daily Paws is part of the Meredith National Digital Network. She definitely is not herself and behaving strangely. oh I should mention shadow is our 8 yr old dogue de Bordeaux - he has never had a reaction to anything ever before in his life and has never needed a vet so this was not usual at all for him .. My beautiful Golden was switched from her previous Medicine to this one. I left a lot out but didnt want to make too lengthy post. I feel horrible for listening to the vet without researching this on my own. Animal Drug Safety Communication: FDA Alerts Pet Owners and Veterinarians About Potential for Neurologic Adverse Events Associated with Certain Flea and Tick Products, How to Report Problems with Flea and Tick Products, An official website of the United States government, : He is fully housebroken and just had a running stool accident in the house. Head bobbling and hind legs unable to support her - as if she were really drunk. They could either keep her there for observation or I could take her home to observe her. Did you go to the vets or not? I am convinced this medicine is HORRIBLE and is causing this. I will be speaking to vet to switch to something else. Thursday morning was an awful beginning of the day for our boy. After the ER visit and a visit with our regular vet today, they concluded he is having neurological issues and that is why he cannot walk. I switched all three of my dogs to simparica trio and ironically my one that is a simi feral h/w+ hound disappeared. What do I do? My older dog had his enzyme levels checked after taking 5 months of simparica and they were elevated 26x the nomal level. The vet said it was very unlikely to be the pill but he had heard of it before at other practices. Simparica, Nexgard, Bravecto and Credelio are part of a group called Isoxazoline drugs. Some adverse reactions to Simparica include tremors, decreased awareness of body movement, loss of control over bodily movements, problems blinking, and/or seizures. and now i'm on an hour by hour let's see if she will perk up. She is only 6 and was so full of life and energy. Bravecto has six topical solutions for dogs by weight/size. He had never pooped in the house and now he does every time he has to be put in his indoor pen for us to leave or sleep. Do you think that Simparica could cause excessive licking by my dog. She didn't make it to the next day and died overnight. All said, we are over $8K into vet bills and growing, Given that he had no noted medical issues prior, his vet and the urgent care vet both feel is was likely the Simparico. Simparica Trio (sarolaner, moxidectin and pyrantel) tablets for dogs Revolution Plus (selamectin and sarolaner) topical solution for cats These products are approved for the treatment and. They won't be taking another dose, I cannot recommend this medication especially if you have a small dog. She spent 4 nights at the University of Auburn emergency room and vet clinic. Twice I have seen his eyes roll into the back of his head (petti-mal seizure?) It is like night and day compared to her regular personality or demeanor. I'll be spreading the word. Later in the fall I noticed some leg tremors when she squatted. 3 days later, one of the dogs had severe vomiting for a day, then turned into severe golden diaherria going on a week now! That was when I lived in Fort Lauderdale. Because this ingredient works differently on invertebrates than mammals, however, Simparica for dogs has been proven safe during field trials. I'm so sorry. Hello to everyone and I am so sorry we had to meet under these circumstances. Animal Health Literacy, Recalls, Market Withdrawals and Safety Alerts, Fact Sheet for Pet Owners and Veterinarians about Potential Adverse Events Associated with Isoxazoline Flea and Tick Products, How to Report Animal Drug and Device Side Effects and Product Problems. The day after administering drug he had two incapacitating seizures. The door is open , its where he prefers to sleep on a doggie bed . On 08/06 she threw up. Heres what you need to know about why cats purr and what your cat may be telling you when her motor is running. I have another dog, but gave him Frontline and he's fine. This medication is generally well tolerated in most pets. And how long for this sheet to get out of the dogs system??? Our vet pushed this new drug for this tick season claiming the drug we used previously they had 11 dogs in the previous year were diagnosed with Lyme disease and they no longer had confidence in that drug. I just hope he has a turn around . My sweet, funny, smart as can be baby girl died on 9/26/20. They want another blood draw in 3 weeks to see where she is. However, they are possible, so it is better to know they might happen. Around 9pm he was barely able to jump up onto the couch and was extremely hesitant to go up the steps. Vet trip and meds $400! My best friend's new puppy has had diarrhea for 14 days after taking one dose of Simparica. We took him to vet and they gave nausea meds and kept him overnight. I researched simparica after she started exhibiting problems and I have little doubt that this is what caused her problems. His vet doesn't think it has anything to do with the Trifexis but I cannot help but think it IS because he was just fine the day before I gave it to him! I have always used topical tx. I will use Sentinel and Pet Armor on her as this is what I have always gjven my dogs with no problems. It causes paralysis that leads to death of hookworms and roundworms. Trifexis and Simparica are available only with a prescription from your veterinarian. I am hoping it is almost all out of her system. My 5 year old Fox Hound isnow drinking lots of water and urinating in the house! Will not be using this treatment again!!! Decreased conscious proprioception. He was in excellent health prior to this incident. We have never had issues with him peeing in the house - EVER, and he peed in my office. Tick titer came back a light positive which lab said was specifically false due to the recent lyme x2 booster i was scared in to giving. Wont use again. He also had a blood test done and all was normal. She seems more anxious now and really attached to hubby. He will be laying then start shaking all over..Has tremors every 5 minutes for 2 hours now. If you havent already done so, please call the simparica trio phone number and report your dogs symptoms. We are going back to the Seresto collar next month. Called his vet and they gave no information. Sunday I started watching how much water he was drinking feeling bad that I was restricting him, so I made sure to take him out to pee every few hours. UPDATE We had one normal day on Friday. Hope your dog is doing well .my dog had clear neurological changes after taking Simparica trio .his tounge just hangs out of his mouth now and that was never the case prior to Simparica,also has tremors and shakes he never previously experienced.also major weight gain even though no increase in diet .i decided to take my pet off of simparico even though the vet strongly engouraged we remain on it even though i explained the symptoms and changes I noticed in my pet ! The leaflet inside at least needs to be changed to have the correct information on it. He had to be put to sleep and Im devastated. He hasn't eaten since and grazes on grass like he is a goat. My 11 year old terrier mix has been weak, uncoordinated and pacing up and down the hallway most of the day, sometimes stopping and staring at the wall. Hi i have only had my pup for about a week and a half i took him to vet and asked what would be safe to use since my pup is only about 11weeks old and weighs 4pds (prob less today) i gave him this medicine last nite and wish i would have seen this post sooner Now i pray he makes it thru the night. I am so incredibly upset with myself for trusting my vet and giving my dog this product. Was checking out before using . They had no clue what had happened so again we took him to the er and he checked out fine. Sound familiar? Conclusion Simparica has possibly shown no severe side effects that may concern the health of dogs. Our boy Axel had been on Heartgard his entire life. 300+ Cute Cat Names for Every Kind of Kitty. This simple-to-give oral monthly treatment protects dogs against heartworm disease as well as against ticks and fleas and intestinal worms like roundworms and hookworms. Never happened before. No this puppy hasnt had seizures and I came to this forum to see other problems with this medicine. Our dog has not been given another dose. Being in CT where Lyme disease is high it's a relief to have top shelf protection. Did you do this yourself or let the vet? If fact it specifically states on the product label "Not for use in humans". The next morning, she had uncontrollable tremors and could not walk without falling down. Today she has fallen 2 or 3 times in the last 8 hours). He seems dehydrated. She has been on it for 6 months. After spending the day at the ER Vet where they did bloodwork and several x-rays all coming back normal, they sent her home with Keppra. Thank you. Couple of days ago, I took my other doxie (Maddie) into my vet, for shots, he did the heart worm test and recommended Simparica. Why the vets use this treatment after so many side effects being reported is disgusting. If she comes out of this I will return to heartworm pills and topical flea and tick meds. Anything I can do for him? This sounds so scary. Sarah thanks for your response! If it was due to the Simparica, then it would expected to be resolved within a day or two. He never ever used to do this. I hope it is taken off the market and request that anyone on this thread with a pet who has suffered due to this drug goes to this link from the FDA to officially report their pet's adverse side effects: https://www.fda.gov/animal-veterinary/report-problem/how-report-animal-drug-side-effects-and-product-problems. Gave my dog Charlie Simparica yesterday now he is shaking and panting really bad. I just hope he makes it to his life expectancy . Simparica Trio covers the most common dog parasites and typically costs less than buying separate products. Product Details: Simparica Trio Chewables for dogs. Not known if there be permanent after-effects. It is important to work with your veterinarian to ensure the best flea/tick and heartworm prevention plan for your pets specific needs. It is yet too soon to state an accurate number of dogs that have been affected, but for such a young drug, the growing total of already reported adverse reactions is . They kindly asked that we schedule an immediate check and diagnostic testing at our local vet. I am trying to remain confident that my poor girl will recover. . and you expect people to give this to their beloved pets? Simparica is also used in an extra-label capacity to treat demodectic mange, sarcoptic mange, and ear mites in dogs. We administered the first dose on Wednesday June 1st to our 9 year old bouvier flanders. My little Billy Boy had his first visit to the vet and they gave him Simparica Trio. We ended up encouraging him to eat something by spoon feeding him. I have a vet appointment tomorrow to figure it out. I gave my dog his first dose April 8th. There is a petition in Australia to have this drug banned through change.org, which I've signed. 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